![]() ![]() ![]() This effect was blocked by administration of a benzodiazepine. Purpose: The selective serotonin reuptake inhibitor (SSRI) fluoxetine has been shown to significantly enhance visual cortex plasticity in adult animals. ![]() These results provide physiological, behavioral, and subjective evidence consistent with a model of puberty-specific changes in neurobehavioral systems underpinning emotional reactivity. Greater recall of emotional words following the task was associated with mid-to-late pubertal status, and greater recall of emotional words was also associated with higher peak pupil dilation. Additionally, mid-to-late pubertal children had faster reaction times to all words, and rated themselves as more emotional during their laboratory visit compared to pre-to-early pubertal children. These findings were replicated controlling for participants’ age. Mid-to-late pubertal children also showed smaller sustained pupil dilation than pre-to-early pubertal children after the word was no longer on screen. Mid-to-late pubertal children showed greater peak pupillary reactivity to words presented during the emotional word identification task than pre-to-early pubertal children, regardless of word valence. Participants were asked to identify the valence of positive, negative, and neutral words while pupil dilation was assessed using an eye-tracker. This study investigated pupillary and behavioral responses to an emotional word valence identification paradigm among 32 pre/early and 34 mid/late pubertal typically developing children and adolescents. ![]()
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January 2023
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